Dozens in Labrador defy court order block entrance to MuskratFalls construction site

first_img(People against the flooding for the Muskrat Falls dam block the construction site entrance. Photo: Tom Fennario/APTN)Tom FennarioAPTN National NewsMUSKRAT FALLS, N.L — Dozens of protectors of the land who are trying to stop the  progress of the Muskrat Falls hydroelectric project defied a court order and blocked the entrance to the dam’s construction site forcing workers to stay long after their shift had ended and prevented the next shift from starting for two hours.“You know, sometimes everybody has to suffer and that’s the situation we’re in right now,” said Inuk protestor irk Lethbridge. “We’re standing up for ourselves, we’re no longer willing to lay down.”The group is concerned that the scheduled flooding expected to start this fall will release toxins into the water and carry downstream to where they hunt and fish.See related stories here: Muskrat FallsWednesday night’s action comes on the heels of the Newfoundland and Labrador’s Environment minister announcement that it ordered Nalcor, the province’s energy agency, to clear vegetation away from the flood zone.What isn’t clear is how much will be removed.“We’re not going to make any deals for a few trees to be cut,” said Lethbridge. “We want the entire area cleared of vegetation so there will be no Methylmercury.”“We’re standing up for ourselves, we’re no longer willing to lay down.” Kirk Lethbridge. Photo: Tom Fennario/APTNAccording to a study by Harvard University, methylmercury, a naturally occurring neurotoxin, will seep from the vegetation if the planned flooding of an area along the Churchill river goes ahead poisoning Inuit and Innu country food, such as fish and other wildlife.“Nalcor has been indicating they have no other choice other than to create this flood to protect their investment.” Newfoundland and Labrador Environment Minister Perry Trimper told APTN National News. “They’ve got $7 billion spent on infrastructure now and they are asserting that they need to do this flood,”Trimper emphasized that Nalcor has been told to clear as much vegetation as possible before the flooding and that letters inviting the three Labrador Indigenous groups to take part in an independent advisory council have been sent.“But it’s clear that a lot of people today are clearly not happy because I’ve not stopped the project,” said Trimper.”That’s what so many people are hoping for. But that’s not my responsibility.”People vow to increase action on the ground to force the province to completely clear the flood zone of vegetation. Photo: Tom Fennario/APTNSeeing some compromise on the government’s part has energized people on the Muskrat Falls line.“We have the government of Newfoundland on the run,” said Lethbridge. “And we’re not going to back down from that.”Wednesday’s work stoppage follows a blockade of the site Sunday that lead to a court injunction against people on the line and an early morning raid by the RCMP that resulted in nine arrests.Three people have also joined Inuk artist Billy Gauthier in a hunger strike. They say they will not eat unless the province clears the vegetation and top soil in the flood zone.“I think as this carries on, you will see more Innu taking part in this action,” said David Nuke, as he watches a group of Innu woman set up a tent at the protest camp across the road from the Muskrat Falls gate.For Lethbridge, it was a welcome sight.“We have no fear, the circle is complete, the Innu are with us now. There’s nothing that can stop the people of Labrador now, we’re no longer willing to live in a box,” he said.— with files from Trina Roachetfennario@aptn.ca troache@aptn.calast_img read more

CSIR Ayush to start drive for herbal drugs discovery

first_imgNew Delhi: In a move aimed at promoting traditional medicines, the Council of Scientific & Industrial Research (CSIR) is all set to start a major campaign to discover new drugs from ayurvedic formulations with the help of its three dozen laboratories.An agreement has also been signed between CSIR and AYUSH Ministry to expedite the research work and both the departments have expressed their hope that their joint efforts would help in the discovery of new ayurvedic drugs for curing lifestyle-based new diseases. Also Read – 2019 most peaceful festive season for J&K: Jitendra Singh”As the CSIR has a record of developing herbal medicines, so the expertise of CSIR would help Ayush Ministry in findings out new ayurvedic formulations. The CSIR developed anti-diabetic ayurvedic drug BGR 34 has proved a milestone in curing diabetic disease,” a CSIR official said, adding that it’s a scientifically developed drug that has been produced by completing various medical tests and is proving very beneficial in controlling diabetes. According to the CSIR official, the joint programme would focus on developing new medicines through extensive research work. Also Read – Personal life needs to be respected: Cong on reports of Rahul’s visit abroadThe agreement to explore new herbal drugs was signed by CSIR DG Shekhar C Mande and Ayush Secretary Rajesh Kotecha. As per the pact, both the departments would initiate two programmes – one would be on traditional knowledge inspired drug discovery while the other would be on food age medicine. Notably, both the departments — CSIR and Ayush — have already developed Traditional Knowledge Digital Library (TKDL) in which all the formulae of Ayurveda has been written in many foreign languages.last_img read more

Israel Kills 8 Children While Playing in a Refugee Camp

New York- Israel killed 17 civilians on the first day of Eid El Fitr, eight of whom were children.According to Al Jazeera Arabic, the Israeli military bombed a group of Palestinian children while they were playing in a refugee camp.In a separate attack, an Israeli missile targeted the main gate of Shifa hospital in Gaza City. These indiscriminate attacks come after a 12-hour truce and amid international efforts to reach a humanitarian truce between the Israeli occupation forces and Hamas.The Israeli military onslaught on Palestinians, which started on July 8th, has left more than 1,100 people dead and over 7,000 people injured.The United Nations Security Council held an emergency meeting on Monday night, in which it called for an “immediate and unconditional” ceasefire, allowing for the delivery of urgently needed humanitarian assistance to the Gaza Strip.In a presidential statement, the Security Council expressed its strong support for the call by international partners and Secretary-General Ban Ki-moon for an unconditional and immediate humanitarian ceasefire, and urged all parties to accept and fully implement it into the Eid period, marking the end of the Muslim fasting month of Ramadan and beyond.“The Security Council also calls on parties to engage in efforts to achieve a durable and fully respected ceasefire, based on the Egyptian initiative,” the statement added.© Morocco World News. All Rights Reserved. This material may not be published, rewritten or redistributed read more

ISIS Combatant Posts Gory Pictures Threatens Morocco

Casablanca- Moroccan ISIS combatant Mohammed Hamdouch, Alias Abou Jandal Al Maghribi, recently shared a gory picture on social media through which he sent a message of terror to Morocco.In one of the pictures he shared, Hamdouch appears pinching his nose next to a crucified body. According to a placard hanging on his body, the crucified man is Youssef Rahal.According to LE360, Hamdouch threatened the Moroccan King, as well as political institutions and representatives of Morocco abroad for their “support of Saudi Arabia and Libya.” In addition, Hamdouch said that many areas in Morocco will soon host training camps for ISIS combatants, according to the same source.In the same context, Ahmed Chaara, another Moroccan ISIS fighter, was arrested in Turkey thanks to the joined efforts of French and Turkish security services.Amidst the terror that ISIS terrorist threats against Morocco have spread in the kingdom, the Royal Armed Forces have been mobilized in all corners of the country to deter terrorist from attacking its strategic sites. read more

Visiting desperate refugees in Darfur UN official appeals for more global aid

On a visit to desperate widows and small children living under trees in a dry river bed and to families huddled in miserable tiny twig shelters in squalid villages in Sudan’s strife-torn Darfur region, the top United Nations refugee official has called on the international community to contribute more money for humanitarian relief.“These people desperately, desperately need the kind of assistance we provide,” Acting UN High Commissioner for Refugees (UNHCR) Wendy Chamberlin said yesterday on the third day of a five-day visit to the region. “UN agencies simply do not have the funding to provide them the assistance they desperately need to survive.”The group in the river bed and the villagers had been refugees in neighbouring Chad, which Ms. Chamberlin is to visit today and tomorrow, and mobile teams from UNHCR are fanning out into the countryside and the desert looking for displaced people and refugees who have returned to the country but are scared to go to their destroyed villages.“We visited two villages, one Arab and one attacked by Arabs, but in both villages families had started to come back,” she said at the end of a gruelling day in the sweltering heat of Darfur, an area the size of France and where a rebellion that began two years ago, partly in protest at the distribution of economic resources, has been compounded by armed militia attacks on villages, uprooting more than 2 million people. Some 200,000 of these fled into Chad.“They came back from Chad for a variety of reasons – because conditions were worse along the border there, because the Sudanese Government told them to come back to receive UN aid, because they wanted to be close to their land,” Ms. Chamberlin said. “Whatever the reason, they are desperate and they have no aid and we, as the UN refugee agency, have a duty to assist returned refugees.”She added that she was haunted by the tales she heard. Zaina Abakar, a 35-year-old widow with three children, told her that she and others living in the river bed have to eat seeds they find on the ground, seeds that are so tough they have to be boiled for three days.Ms. Abakar said all the women and their children live in fear and were frightened even by the arrival of Ms. Chamberlin’s helicopter. “We are living here, yes, but we are scared,” Zaina stressed, cuddling her year-old baby boy Mohammed. “We are scared of everything. When we saw your plane (helicopter), we thought of running away. Whenever anything happens we think of running.” She begged the UN to bring food, water, and above all, security.Ms. Chamberlin cautioned against hopes of any quick end to the Darfur crisis. UNHCR and other aid organizations “are here for the long term. People we have seen are terrified to go back to their villages.“There was still a great deal of fear in their faces because of the things they have been through. Clearly they want and need more protection from the African Union troops, from the UN and particularly the protection the UN refugee agency is best capable of providing,” she added. read more

SMMT supports West Midlands companies

All completed surveys will be entered into a prize draw to win a ticket to SMMT’s Annual Dinner which will be held 24 November 2009.The questionnaire can be accessed hereClick to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window) The Society of Motor Manufacturers and Traders (SMMT), is working with Accelerate to support the West Midlands Task Force with a project to assess the impact of the economic downturn on companies in the region.  The project will take into account the views of businesses in the region and use the information gathered to help formulate a regional strategy. The scrutiny of businesses based in the region is essential to the success of understanding and addressing the specific regional business and employment issues associated with the global economic downturn. The questionnaire provides an excellent opportunity for businesses to voice their concerns and help themselves to minimise the impact and ensure resilience in the region over the long-term. read more

Jovanka Radicevic Gyori I want to play Final in Podgorica

Budućnost PodgoricaEHF Champions LeagueGyori handballJovanka RadičevićPodgoricaValcea ← Previous Story Petar Metličić goes to HC Montpellier Next Story → C.O Zagreb away series in SEHA: Two wins and defeat in Cetinje Right winf of Hungarian Gyori, Jovanka Radicevic admits her wish to play at the EHF Champions League Final against her first team, Buducnost in Podgorica:-Tension began since moment, when they asked us, how many tickets we need. Of course, we feel the pressure, but that isn’t a reason not to show what we can. With our fans, it will be much easier – said Montenegrian NT player, before the first semi-final clash in Romania against Oltchim Valcea.– We practiced in the same way as before. Oltchim is TOP team with TOP individuals, which are very good in play “1 on 1”, but we will stay focused on our tactics. I believe that strong defence with smart attack we will make a good result before the second match in Hungary.Buducnost VS Larvik?– Buducnost plays very good with fantastic Clara between the posts. On the other side, Larvik is better and better after weak start of the season. Norwegian team is very experienced, many years together. I expect that will be indecisive until the last minutes. I would like to play in the Final and to feel the atmosphere in the sold “Moraca” in Podgorica, why not.  I want to play in the Final, nevermind where – says Joka for Balkan-Handball.comLarvik – Budućnost 16.45h (Arena Sport 1, ehftv.com) Sunday:Oltchim – Gyori 17.00h (ehftv.com)photo: http://www.gyorietokc.hu read more

Wasp33B la planète la plus chaude de lUnivers

first_imgWasp-33B, la planète la plus chaude de l’UniversDes astronomes viennent de découvrir la planète la plus chaude connue à ce jour. Il s’agit d’une planète gazeuse géante qui atteint les 3.200°C, une température supérieure à celle de nombreuses étoiles. La planète WASP-33b a révélé récemment, grâce aux mesures effectuées avec le télescope Herschel des îles Canaries, qu’elle possédait une température de près de 3.200°C. Cette température incroyable est supérieure à celle de certaines naines rouges et supérieure à celle de la planète WASP-12b qui détenait le précédent record avec 2.300°C.À lire aussiL’expansion de l’Univers est bien plus rapide que ce que l’on pensait, voici ce que ça changeCette planète, découverte en 2006, a vu son existence confirmée en 2010 et serait 4,5 fois plus petite que Jupiter, précise le New Scientist. WASP-33b pourrait aider les astronomes à en apprendre davantage sur les planètes très chaudes, indique Drake Deming de la Nasa.En effet, de nombreuses questions se posent encore sur ces planètes dont les couches atmosphériques supérieures semblent plus froides que les couches profondes. La chose est surprenante puisqu’elles devraient être réchauffées par les importantes radiations émises par les étoiles autour desquelles elles gravitent.Le 20 janvier 2011 à 18:16 • Emmanuel Perrinlast_img read more

Samsung propose une mini caméra de surveillance Wifi

first_imgSamsung propose une mini caméra de surveillance WifiSamsung présente une caméra de surveillance WiFi destinée au grand public pour garder un œil sur son foyer, où que l’on se trouve.Samsung propose au grand public de faire de leur intérieur un mini Secret Story. En effet selon Übergizmo, le constructeur proposera à la vente une mini-caméra WiFi, destinée à surveiller son intérieur et garder un œil sur son domicile si l’on est en déplacement ou au bureau. À lire aussiClavier virtuel : quand vos doigts se transforment en clavierCette caméra, selon Samsung, prend 30 secondes à être configurée et rattachée à son réseau domestique via un routeur livré avec l’appareil. Ensuite, vous devez vous enregistrer sur un site dédié avec nom, identifiant et mot de passe pour accéder simplement depuis un navigateur à la vidéo. Une solution pour surveiller son enfant lorsqu’il dort, ou son appartement lorsque l’on est en voyage.Mais il est impossible d’être connecté 24 heures sur 24 sur son ordinateur, à moins d’être très sérieusement paranoïaque. Là encore, Samsung à la solution. L’appareil est équipé d’un détecteur de mouvements. S’il la caméra capte un déplacement dans son champ de vision, elle enregistre et publie les instants correspondants sur votre compte YouTube, tout cela bien sur en mode privatisé et vous envoie une notification d’alerte.L’entreprise n’a pas encore communiqué sur la disponibilité ou le prix de cet appareil. Le 11 novembre 2011 à 18:11 • Maxime Lambertlast_img read more

Bad weather for Bahamas TCI ahead of Hurricane Irma

first_img August 30th – One Year since Hurricane Irma named Recommended for you Related Items:#HurricaneIrma, #magneticmedianews, #TropicalDepression, #TropicalStormJose Facebook Twitter Google+LinkedInPinterestWhatsApp#Bahamas, September 5, 2017 – Nassau – WINDS MAY GUST TO MORE THAN 25 KNOTS AND VISIBIITY REDUCED TO LESS THAN 3 NAUTICAL MILES DURING HEAVY SHOWERS OR THUNDERSTORMS.GENERAL SITUATION: A TROUGH LINGERING OVER THE BAHAMAS WILL CONTINUE TO GENERATE UNSETTLED WEATHER OVER THE ISLANDS.ALL AREAS:  SMALL CRAFT SHOULD BE ALERT FOR GUSTY WINDS AND HIGHER SEAS IN OR NEAR HEAVY SHOWERS AND THUNDERSTORMS.In addition to #HurricaneIrma and #TropicalStormJose there is also newly formed #TropicalDepression 13.#MagneticMediaNews New, stringent posture on illegal construction makes fines, personal demolition and possible deportation legal says PDM Minister, law now passed Facebook Twitter Google+LinkedInPinterestWhatsApp FortisTCI announces bid to hike electricity bills, cites record $42m response to hurricanes as destabilizinglast_img read more

UPDATE Week could bring medley of winter weather

first_imgCheck out user-submitted photos of snowfall in Clark County.Do you have photos of the snow? E-mail them to matt.wastradowski@columbian.com to get them included in the gallery.After fleeting snow flurries teased much of Clark County over the holiday weekend, forecasters predict another system will bring a strong dose of wintry weather during the next couple of days.Expect more than snow this time around: An active week could also bring ice, sleet, heavy rain and wind to the Portland-Vancouver area.“We could have the whole shebang, pretty much,” said Liana Ramirez, a meteorologist with the National Weather Service in Portland. “It will be really interesting to see how it pans out.”The best chance for significant snow at low elevations arrives Tuesday night. As much as a few inches could fall in places Tuesday night into early Wednesday, according to the weather service. But if anything sticks, it won’t stay long — later Wednesday, temperatures will rise, and the snow level will shoot back up to nearly 4,000 feet, according to the weather service. That transition period is when ice, sleet or freezing rain could develop, Ramirez said.The shift won’t mean calmer weather. Heavy rain continuing into the weekend will cause some rivers and streams to rise by the end of the week, according to the weather service. “Several inches” of rain could fall between Wednesday and the beginning of next week, Ramirez said.Forewarned is forearmedMonday’s wintry prospects prompted the weather service to issue a wide array of special statements and warnings. Vancouver alone saw five posted — among them a winter weather advisory and a winter storm watch. Forecasters wanted to get the word out ahead of what could be a messy morning commute Tuesday and Wednesday, Ramirez said.last_img read more

In spite of it all some will act against best interests

first_imgPeople with higher levels of guilt, which is a concern for other people and a fear of violating social norms, scored lower on spitefulness; people with higher levels of shame, which is more a sense of inadequacy and failing, scored higher.These scenarios were written for a research study to gauge spitefulness levels among 1,200 people. (Not all scenarios were used in the study.)1) It might be worth risking my reputation in order to spread gossip about someone I did not like.2) If I am going to my car in a crowded parking lot and it appears that another driver wants my parking space, then I will make sure to take my time pulling out of the parking space.3) If my neighbor complained that I was playing my music too loud, then I might turn up the music even louder just to irritate him or her, even if it meant I could get fined.4) If my co-workers were going to get larger raises than me, then I would prefer it if none of us received raises.5) If I had the opportunity, then I would gladly pay a small sum of money to see a classmate who I do not like fail his or her final exam.6) There have been times when I was willing to suffer some small harm so that I could punish someone else who deserved it.7) I would rather no one get extra credit in a class if it meant that others would receive more credit than me.8) If I opposed the election of an official, then I would be glad to see him or her fail even if their failure hurt my community.last_img read more

Aquis to establish and develop Australian eSports business

first_imgAustralian-listed casino operator Aquis Entertainment Limited has revealed plans to establish and develop an eSports business, to be known as QeSports.Aquis, which owns and operates Casino Canberra in the Australian Capital Territory, will partner with Executive Sports and Entertainment Pty Limited (ESE) to create the QeSports brand, which will focus on providing various forms of infrastructure around which the eSports industry can grow.The business will include an eSports advisory, player and talent management agency including the provision of advice, media training and partnerships to eSports players; eSports event and tournament creation and management; and eSports arena development in Australia via affiliations and partnerships with eSports organizations.Aquis will hold 70% of shares in QeSports with ESE holding the other 30%, while a principal of ESE, Rohan Sawyer, will become QeSports CEO.Aquis will also provide initial financing to QeSports of up to AU$2 million via a shareholder loan. Drawdown of the loan will be incremental, subject to QeSports meeting agreed milestones in its business plan.Discussing the new partnership, Aquis Entertainment CEO and Executive Director Jessica Mellor said, “Aquis Entertainment’s vision is to provide Australia with next generation entertainment and our move into the eSports market is very much in line with that strategy.“Australians are well known for their passion for traditional sports and we’re starting to see this passion translate to eSports as the sector matures.“Two-thirds of Australian eSports fans are aged 18 to 34 and that’s a market segment we know very well. This, coupled with our experience in entertainment venue operations, puts us in a strong position to meet a wide range of expanding needs in the eSports space.”Aquis said it will run QeSports as a separate business from Casino Canberra. Load More RelatedPosts Revenue falls, losses widen for Aquis Entertainmentcenter_img Casinos can innovate – and win new fans Caesars links with Japanese arcade game giant Taito for first US e-Arcade sports competitionlast_img read more

FCA to consult on protecting retirement income when accessing pension freedoms

first_imgThe Financial Conduct Authority (FCA) yesterday (28 January 2019) launched a consultation on proposed measures designed to protect retirement income when individuals access pension freedoms.The consultation, which will be collecting feedback from stakeholders until 5 April 2019, proposes that pension scheme members who do not take financial advice should be offered a selection of investment pathways, designed to broadly suit their objectives. Members will be able to choose from four objectives, and their investment option will then be matched to their choice.The FCA further recommends that pension investments are not defaulted into cash savings unless the member actively chooses to take this path.Steve Webb, director of policy at Royal London, said: “The big outstanding challenge around pension freedoms is not people with large pots blowing the lot on a sports car, but is about more inexperienced investors with smaller pots leaving them invested in cash for long periods of time or withdrawing them altogether.“These FCA rules are a sensible response to the risk of savers sleepwalking into seeing their hard-earned savings eroded by sitting in low-return cash investments. But there is still a problem where people cash out the whole pot and transfer it into a cash [individual savings account] or current account. It is clear that reckless caution, not Lamborghinis, is the big outstanding challenge with pension freedoms.”The consultation will also discuss the information included in wake-up packs, which are given to members as they approach retirement. Changes that are being reviewed include the frequency of the wake-up packs’ delivery, the move to prevent marketing material being included and amends to the key features illustration that members receive when entering drawdown.The FCA further seeks to enhance transparency around fees and charges by providing members with information on charges they have paid on their pension pot over the year, expressed as a cash amount.Mark Jaffray, partner and head of defined contribution (DC) consulting at Hymans Robertson, said: “The industry needs to start viewing drawdown as a service rather than a product. People are crying out for more affordable access to advice or guidance around their pension options and personalised investment solutions based around their individual goals will help to provide that. The FCA’s proposal to introduce default investment pathways will be an important step in the right direction, as long as costs are kept low and clearly communicated throughout.“Greater transparency around charging will be a welcome benefit for many. Explaining a clear first year charge in pounds and pence will allow consumers to compare offers more easily across a number of providers and encourage them to actively shop around as a result.“However, it’s important that the FCA doesn’t stop there. We are already seeing parallels in drawdown with the sale of annuities products prior to 2017, where despite an open market option, consumers rarely looked around for the best deal. The FCA addressed this problem by forcing providers to share details of the best available quote in the market for an annuity, actively promoting the value from shopping around. Given that the vast majority of people now opt for drawdown over an annuity product, it’s madness that we don’t have the same measures in place.”The measures featured in the consultation form part of the FCA’s wider pensions strategy and follow on from its Retirement outcomes review report, published in the summer of 2018.Proposed changes to wake-up packs, retirement risk warnings, reminder requirements and the annuity prompt are expected to be effective from 1 November 2019. Amendments concerning making the cost of drawdown products clearer and making comparisons easier will be implemented from 6 April 2020, subject to consultation.Christopher Woolard, executive director of strategy and competition at the FCA, said: “The pension freedoms give consumers more flexibility in how and when they can access their pension savings, but that also means they have to make more complicated choices.“Our Retirement outcomes review identified that many consumers are focused only on taking their tax-free cash and take the path of least resistance when entering drawdown. This can often mean that the rest of their drawn down pension pot is not invested in a way that meets their needs and intentions. We found that around one in three consumers who have gone into drawdown recently are unaware of where their money is being invested. This leads to poor consumer outcomes.”Tom McPhail, head of policy at Hargreaves Lansdown, said: “The FCA was presented with a huge regulatory challenge when the former chancellor tore up the retirement rule book in 2014. The pension freedoms have bedded in and are working well, but this review has rightly identified [that] more can be done to help investors make the most of their retirement savings.”last_img read more

Sensex weekly gain at 378 pts Reliance up 45 on day Sun

first_imgAn Indian woman speaks on her phone while walking past a Bull sculpture outside the Bombay Stock Exchange (BSE) in Mumbai on February 6, 2018. Asian stocks plunged on February 6 after a record-breaking loss on Wall Street, extending a global rout as panicked investors fret over rising US borrowing costs and take profits after months of market euphoria.INDRANIL MUKHERJEE/AFP/Getty ImagesIndia’s benchmark stock index Sensex marked a weekly gain of nearly 380 points as trading wound up on Friday.The BSE Sensex settled 12.53 points, or 0.03 percent, higher at 36,386.61. The broader NSE Nifty inched up 1.75 points, or 0.02 percent, to 10,906.95. trading was flat on on Friday after a volatile session as investors largely stuck to index heavyweights despite positive global cues.Led by Sun Pharma, BSE Healthcare index tanked 2 percent on Friday, while telecom stocks also saw heavy selling pressure, losing more than 3 percent.During the week, the 30-share Sensex gained 378.77 points, or 1 percent and the Nifty rose 112 points, or 1.02 percent.Sensex rises 12.53 pointsNifty up 1.75 pointsSun Pharma drags healthcare stocks Rupee falls marginallyDomestic markets seen range-bound in near termReliance Industries was the biggest gainer on Sensex in Friday’s session, spurting 4.43 percent, after the company became the first Indian private sector company to report a quarterly profit of more than Rs 10,000 crore following record earnings from petrochemical, retail and telecom businesses.Other gainers included Kotak Bank, HCL Tech, ONGC, Asian Paints, Vedanta, HDFC Bank, Bajaj Finance, Maruti and TCS, gaining up to 1.41 percent.”Domestic indices failed to absorb the rebound in global market as plunge in pharma stocks and weak rupee dragged the sentiment … Global headwinds continue to dictate a range-bound movement in the market while any green shoots in quarter earnings provide opportunity to accumulate.”Sun Pharma was the top loser, cracking 8.58 percent, on reports of fresh allegations by a whistleblower against the company.Domestic markets range-bound in near term”Domestic indices failed to absorb the rebound in global market as plunge in pharma stocks and weak rupee dragged the sentiment,” said Vinod Nair, Head of Research, Geojit Financial Services. “Global headwinds continue to dictate a range-bound movement in the market while any green shoots in quarter earnings provide opportunity to accumulate,” he added. RIL’s 41st AGM: Biggest highlights On a net basis, foreign portfolio investors (FPIs) purchased shares worth Rs 842.13 crore Thursday, while domestic institutional investors (DIIs) were net sellers to the tune of Rs 727.46 crore, provisional data available with BSE showed.According to analysts, global trade tensions and risk of recession will cast a cloud over the sentiment, while lack of major triggers in the domestic market could see range-bound movement in the near term.The rupee, meanwhile, depreciated 10 paise against the US dollar to 71.13 intra-day.(With inputs from PTI) Close IBTimes VideoRelated VideosMore videos Play VideoPauseMute0:01/1:09Loaded: 0%0:01Progress: 0%Stream TypeLIVE-1:08?Playback Rate1xChaptersChaptersDescriptionsdescriptions off, selectedSubtitlessubtitles settings, opens subtitles settings dialogsubtitles off, selectedAudio Trackdefault, selectedFullscreenThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window. COPY LINKAD Loading …last_img read more

Money laundering to be ruled with iron hand

first_imgACC logoThe Anti-Corrupt Commission (ACC) would take stringent measures against people involved with money laundering, ACC chairman Iqbal Mahmood said on Wednesday.Preventing money laundering is a must to achieve the status of a developing country, he said.Iqbal made the remark while speaking at a human chain to mark Corruption Prevention Week 2018 in front of the National Press Club.Claiming that the situation has improved in regards to tackling graft, Iqbal said creating consciousness and unity among people is vital to eliminate corruption.Senior ACC officials were also present at the human chain.last_img

Analysis On Texas High Property Taxes Theres Plenty Of Blame To Go

first_img Share Marjorie Kamys Cotera for The Texas TribuneA lawmaker reads a flyer with property tax information that was distributed to Texas House members’ desks on August 12, 2017.Texas state senators are touchy, touchy, touchy when it comes time to hand out blame for rising property taxes.They’ve spent a decade hacking away at the state’s share of public education spending, and their current refrain is that the local districts have run amok by raising property tax bills.What they don’t like is having anyone — especially an official someone — pointing out the relationship between the state’s declining per-student education spending and the rise in local property taxes.To cap that, the latest flare-up came from Tarrant County, the most populous red county in the Republican state of Texas — a big jewel in the GOP’s crown and an exception to the trend of urban counties becoming more Democratic.  The official someone, this time, was Tarrant County Judge Glen Whitley, a Republican who’s been on the commissioner’s court for more than two decades. According to the Fort Worth Star-Telegram’s Bud Kennedy, Whitley told a local crowd last week that the increases in their property taxes were driven by the state’s failure to pay its share of public education costs.He put a page from the current state budget on screen for the crowd, so they could read this increasingly infamous gem on page III-5: “Property values, and the estimates of local tax collections on which they are based, shall be increased by 7.04 percent for tax year 2017 and 6.77 percent for the tax year 2018.”Sounds awful, right? Be fair: It’s not the state dictating a tax rate, but the state’s estimate of what the school districts are going to do. The local tax revenue helps determine state spending on education.A small pack of local state senators, in a letter sent to the Star-Telegram and copied to the rest of the state news media, said Whitley was “dishonestly” suggesting that the state was setting local property tax rates.“Let’s set the record straight,” they wrote. “Local property tax rates are set by locally elected officials. Period. They are not determined by an informational rider in the state budget as Judge Whitley dishonestly suggests. He well knows our school finance formula dictates that local property tax revenue go into the system first, with state funding added on top. This has been the case since the 1940s. Local property tax collections dictate the state’s share of education funding — not vice versa.”That’s correct, as far as it goes. But local public education spending — and the property taxes that fund it — have risen over the last decade as the state’s share of public education has fallen. “Dictate” is a strong word to use on school districts trying to make up for the state’s spending cuts.And here’s a pro-tip for students of subterfuge: Tell the truth while you’re lying. Those senators say, truthfully, that state spending in the current budget is up significantly — $5.8 billion more than it was in the previous two-year budget, according to the Legislative Budget Board. They don’t say, however, that the state’s share is sliding from 43.7 percent of the total Foundation School Program spending in 2016 to 38 percent in 2019. Or that the state covered 48.5 percent of the total as recently as 2008 — ten years ago. Or that, thanks to the ever-increasing number of Texas school kids, state spending per student has fallen even as total state spending has risen.Local spending in 2008, according to the LBB, was 51.5 percent of total local-state education spending. In 2019, it’ll be 62 percent.One more set of numbers to round this out: Local spending, according to the LBB, is rising $6.9 billion from the 2016-17 biennium to the current 2018-19 biennium. The state’s part is actually dropping $1.1 billion from the first two-year budget to the second.Spending from state tax dollars is down. Spending from local tax dollars is up. Overall spending, which does go through the state budget and funding formulas — giving state lawmakers scads of political wiggle room — is up.Student populations are exploding, too, but that’s another set of numbers for another day.The bottom line is that Whitley has a strong argument. State lawmakers are not solely to blame for the increasing burden on local taxpayers, but they are certainly as responsible as anyone else. The senators are right about this: There’s certainly no reason to let local school boards, county commissioners and city council people off the hook, because those are, in fact, the people who levy property taxes.But don’t let state senators skate, either, even though they seem to be better at it than most of the people competing in PyeongChang right now. When the state stops paying its share, locals — the property tax folks — have to find the money somewhere. They’re finding it by taxing property owners.Blame all of them. It’s only fair.last_img read more

Mapping subcellular temperature profiles with geneticallyencoded thermosensors

first_img More information: Genetically encoded fluorescent thermosensors visualize subcellular thermoregulation in living cells, Nature Methods (2013) DOI: 10.1038/nmeth.2690AbstractIn mammals and birds, thermoregulation to conserve body temperature is vital to life. Multiple mechanisms of thermogeneration have been proposed, localized in different subcellular organelles. However, visualizing thermogenesis directly in intact organelles has been challenging. Here we have developed genetically encoded, GFP-based thermosensors (tsGFPs) that enable visualization of thermogenesis in discrete organelles in living cells. In tsGFPs, a tandem formation of coiled-coil structures of the Salmonella thermosensing protein TlpA transmits conformational changes to GFP to convert temperature changes into visible and quantifiable fluorescence changes. Specific targeting of tsGFPs enables visualization of thermogenesis in the mitochondria of brown adipocytes and the endoplasmic reticulum of myotubes. In HeLa cells, tsGFP targeted to mitochondria reveals heterogeneity in thermogenesis that correlates with the electrochemical gradient. Thus, tsGFPs are powerful tools to noninvasively assess thermogenesis in living cells. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Measuring temperaure inside cells. Credit: Steven H. Lee © 2013 Phys.org Mitochondrial cooperatives Journal information: Nature Methods The key to building this new sensor is a protein known as TlpA, which is made by Salmonella. The normal operation of TlpA is as an autoregulatory repressor that senses temperature to control transcription. At around 37 degrees C, it undergoes rapid and reversible structural transition to an unfolded monomer. By fusing the fluorophor region of GFP to TlpA, the researchers were able to make the fluorescence spectrum of GFP temperature dependent. The final step was to join the fusion protein to sequences that could target the protein to either the mitochondria, endoplasmic reticulum (ER) or plasma membrane.The researchers were then able to simultaneously image the temperature-sensitive GFP along with the mitochondrial membrane potential indicator dye, JC-1. They found that that elevations in temperature and potential were highly correlated. Perhaps that is not so surprising, but it is the nature and order of these correlations where potency might be derived. They also confirmed this link using another genetically-encoded sensor (ATeam26), along with fluorescence resonance imaging (FRET)to measure ATP. Since ATP is synthesized primarily by an electrochemical pump during oxidative phosphorylation, its production should reflect the mitochondrial proton gradient as seen by JC-1.The characteristics of these complex sensors were vetted by studying the well-known phenomenon of thermogenesis. The researchers looked at brown fat adipocytes, and also avian skeletal muscle, which is the preferred method of heat generation in bird species. The full power of this technology will arguably best be brought to bear when it is applied to the brain. The thermodynamics of spiking neurons has been driven experimentally mainly by rather imprecise external temperature sensors. With a better handle on temperature changes, not just inside and outside axons, but inside the glial cells which myelinate them—and also carry a significant fraction of the spike energy, possibly as phase transitins—a better understand of neural transmission may be had.Where neurons connect, the role of presynaptic mitochondria as transactors of electro-mechanical spike currency into chemo-mechanical vesicle dynamics might now be imaged in telling detail. Similarly on the opposed side of the synapse, where mitochondria are scuttled as a function of minipotential to sop or source calcium, ATP and heat itself, their broader function as hidden communicator of information and power not just at the level of synapse, but cell, may be revealed. Infrared thermography is generally not suitable for imaging fine features in cells. Its spatial resolution is greater than 100μm and it detects only the surface temperature of the object. To measure organelle temperatures, you need a sensor that operates on their scale. A quantum dot or nanodiamond sensor perhaps 100nm wide could be incorporated into a cell by endocytosis, but once inside, it can go anywhere. These sensors can measure intracellular fluctuations of just 0.05 Kelvin (and outside the cell 0.0018), but unless they remain right at heat producing structures in the cell, they will probably only sense uniform thermal background. The reason for this is that not only does any heat generated by these organelles diffuse away rapidly, the organelles themselves like to move. It is worth mentioning that a fascinating paper appeared not long ago on the Arxiv server which attempted to measure how far the effects of the hydrolysis of a single ATP molecule could be felt. The number they came up with is the same size as the sensors we just mentioned, 100nm.The first direct links between organelle function and temperature were made earlier this year by researchers from Japan. They developed a fluorescence lifetime method which used a polymer based thermometer. The temperature resolution they obtained was 0.2 C (apologies for the unit mixing) while the spatial resolution was diffraction limited. These researchers were able to show that the nucleus and centrosome were significantly hotter than other parts of the cell. We generally think of cilia and their associated centrioles as being chemically or molecularlly controlled. Watching their response as a function of temperature may cast their primal role in a new light. While these studies are nice, what sets apart the new research (also done by a Japanese team), is that they could genetically encode a protein-based sensor, target it directly to different organelles like the mitochondria, and then simultaneously measure membrane potential and energy production to correlate temperature increases to the intrinsic function of the organelle. (Phys.org) —If you asked a biologist what any given cell is going to do next, they might ask you first to tell them its electrical potential, oxygenation, pH, osmolarity or glucose concentration. Depending on how finely-scaled your answer might be, they might be able to predict anything from firing an action potential or entering mitosis, to undergoing apoptosis. But what if you knew the subcellular temperature profile in such detail that each mitochondria, centriole and even regions of the endoplasmic reticulum could be read as easily as a mother her child’s fever? That question now drives some of the most exciting research in biology. This year several groups have come up with ingenious thermometric methods ranging from fluorescence lifetime microscopy to exotic diamond nanosensors employing nitrogen vacancy centers. The latest breakthrough, just published in Nature Methods, describes a method that uses a genetically-encoded sensor built from green fluorescent protein (GFP) that is fused to a thermosensing protein borrowed from Salmonella. The researchers used this construct to probe thermogenesis in brown fat mitochondria, and perhaps most astoundingly, were able to correlate temperature with both mitochondrial membrane potential and ATP production. Citation: Mapping subcellular temperature profiles with genetically-encoded thermosensors (2013, October 16) retrieved 18 August 2019 from https://phys.org/news/2013-10-subcellular-temperature-profiles-genetically-encoded-thermosensors.html Explore furtherlast_img read more

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